Explanation has been an important topic of study in philosophy of science, in epistemology, and in other areas of philosophy. In parallel, psychologists have been studying children’s and adults’ explanations, including their role in inference and in learning. This entry reviews recent work that begins to bridge the philosophy and psychology of explanation, with sections introducing recent empirical work on explanation by philosophers, formal and functional accounts of explanation, inference to the best explanation, the role of explanation in discovery, and the implications of empirical work on explanation for the “negative program” in experimental philosophy.